In Vitro Photoprotection and Functional Photostability of Sunscreen Lipsticks Containing Inorganic Active Compounds

Titanium dioxide (TiO2) is a safe inorganic ultraviolet (UV) filter with activity against UV damage. However, the recombination of carrier’s charge and tendency for TiO2 aggregation are main disadvantages. Substrate supports, such as mesoporous silica, biocompatible strategies to incorporate TiO2, altering its interaction skin. Since lips sensitive adversities environment, including radiation, application lipstick sunscreens great importance expected provide protection this particular area sunburn photoaging, among other unfavorable responses unprotected exposure. We investigated in vitro photoprotective efficacy photostability formulations containing incorporated into silica (SBA-15). The samples were base; SBA-15; (free form); SBA-15. was characterized using Labsphere UV2000S. Lipsticks irradiated Suntest CPS+ chamber evaluate functional photostability. Lipstick base SBA-15 alone did not display efficacy. sample 10.0% generated greater sun factor (SPF) value compared one only state). Our findings suggest that + can be considered broad-spectrum ingredient innovative sunscreens, particularly photoprotection lips.